New Histophatological Finding About Data Destroying Amyloid Black Holes in Hippocampus Following Olfactory Bulb Lesion Like as the Universe

نویسندگان

چکیده

Background: Many infinite theories have been suggested to explain memory loss in neurodegenerative diseases. However, there is no data that iron-containing neurofibrillary networks can cause neuron death and erase the of neurons, just like black holes space. Objectives: Ths study aimed investigate electromagnetic properties iron-loaded formed hippocampus as a result damage olfactory nerves, space, well whether they loss. Methods: All rats were tested with star maze performance before, 3 weeks, months after surgery. The used obtained from subjects experimental groups who had followed up for control (GI; n = 5), SHAM (GII; 5) only frontal burr hole, (GIII; 15) animals bulb lesion. bulbs examined by stereological methods. Olfactory volumes, degenerated densities hippocampus, numbers hippocampal estimated quantitatively, results statistically analyzed 1-way analysis variance (ANOVA). brains universe compared theoretically. Results: mean density, 4.43 ± 0.22 mm3, 42 9 1 mm3 GI, 4.01 0.19 257 78 11 GII, 2.4 0.8 1675 119 34 7 GIII. Latency, distance, speed, path efficiency values all detected. more diminished volume (P < 0.00001) causes apoptotic neurons 0.0001) lesion (OBL)-applied 0.005). Conclusions: Hippocampal holes, which are similar terms their formation processes, may be responsible neuronal losses erasures brain acting These amyloid plaques, loss, will called data-deleting (DADA-Black Holes) paper.

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ژورنال

عنوان ژورنال: Archives of Neuroscience

سال: 2022

ISSN: ['2322-5769', '2322-3944']

DOI: https://doi.org/10.5812/ans-123169